E-MRS Spring 2012 - Symposium K
Surface modifications of carbon-related materials II
Diamond and carbon-based materials (diamond like carbon, carbon nanotubes, graphene, carbon onions,…) show exceptional properties in aqueous solutions with nearly perfect interfaces for bio-chemical sensors or for drug delivery applications.
Grafting of carbon materials for bioapplications...
This symposium focuses on chemical modifications applied to graft surfaces of diamond, nano-diamond particles, diamond-like carbon, graphene, graphite, carbon nano-tubes , and carbon dots with linker molecular layers for realization of bio-sensors, bio-markers, fillers in polymer composites, nanolubricants, drug delivery, separation techniques, and switchable chemical links.
Techniques can span from spontaneous bonding to photo-chemical attachment, electrochemical modifications, to Suzuki-coupling of aryl molecules. Special attention will be drawn to mechanisms driving bonding kinetics such as electron transfer reactions, hydrogen cleavage reactions by nucleophilic molecules and growths schemes which may vary from correlated two-dimensional chain reactions to three dimensional cross polymerization. Hydrogen terminations, surface defects, surface roughness and atomic arrangements of surface carbon atoms are of interest to elucidate bonding mechanisms. Approaches to avoid agglomeration of diamond nanoparticles during surface functionalization reactions will be of particular interest. Aim is to develop basic understanding ranging from the atomic/molecular level to macroscopic properties of modified carbon related surfaces.
The symposium will draw attention towards surface properties of various carbon materials like bonding stability, either of linker molecules or of complex functionalized surfaces with therapeutic molecules, DNA, proteins and enzymes. The electronic interface will be of interest, especially data deduced from spectroscopic measurements which allow to determine surface and interface defect densities, Fermi level pinning and electron transfer rates. Miniaturization of sensor area and application of new detection schemas will be major topics in this symposium.
Diamond nano-particles, CNT and carbon dots are used as biomarkers in drug delivery experiments to monitor propagation of biomolecules. This symposium will therefore include a forum where a) physical properties, b) surface modifications, c) color-center formation, and d) size related limitations of cell penetration will be discussed. Of particular interest will be a discussion on ways to control content and state of doping elements (nitrogen and others) in the interior of diamond nanoparticles.
"Controlled release" of drugs from nano-particles or from AFM tips will be a topic of this meeting taking into account: a) spontaneous release, b) triggered release by light induced bond breaking or c) electrochemical bond-breaking. Finally, a discussion of "bio-compatibility" of carbon related transducers and nano-particles will be of interest for this meeting.
Hot topics to be covered by the symposium
Confirmed invited speakers
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